Reproduction and Development

1. Bo Gao, Jingzhi Guo, Chaowen She, Anli Shu, Maosheng Yang, Zheng Tan, Xinping Yang, Shengzhen Guo, Guoying Feng, Lin He*. Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-1. Nature Genetics. Nature Genetics, 2001; 8(4):386-8.(IF: 40.361, Nature Publishing Group 杂志)
2. Bo Gao, Jianxin Hu, Sigmar Stricker, Martin Cheung, Gang Ma, Kit Fong Law, Florian Witte, James Briscoe, Stefan Mundlos, Lin He, Kathryn S.E. Cheah and Danny Chan*. A mutation in IHH that causes digit abnormalities alters its signalling capacity and range. Nature,  2009; 458(7242):1196-200.(IF: 36.101, Nature Publishing Group 杂志)
3. Hu Y, Zhang X, Jia H, Lai KP, Leong WF, Au BJ, Mishina Y, Chen YG, Biondi C, Robertson E, Xie D, Liu H, He L, Wang X, Yu Q, Li B*.Chau JF, Jia D, Wang Z, Liu Z,  A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response.  Nature Communications, 2012; 3:836. doi: 10.1038/ncomms1832.
4. Ma G, Li L, Hu Y, Chau JF, Au BJ, Jia D, Liu H, Yeh J, He L, Hao A, Li B*.Atypical Atm-p53 genetic interaction in osteogenesis is mediated by Smad1 signaling. J Mol Cell Biol, 2012; 4(2):118-20.
5. Li B, Ling Chau JF, Wang X, Leong WF*. Bisphosphonates, specific inhibitors of osteoclast function and a class of drugs for osteoporosis therapy.  J Cell Biochem, 2011; 112(5):1229-42.(IF: 3.122)
6. Lai KP, Leong WF, Chau JF, Jia D, Zeng L, Liu H, He L, Hao A, Zhang H, Meek D, Velagapudi C, Habib SL, Li B*.S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response.  EMBO J, 2010; 29(17):2994-3006.(IF: 10.124)
7. Liu H, Li B*. p53 control of bone remodeling. J Cell Biochem, 2010; 111(3):529-34.(IF:3.122)
8. Wang X, Zeng L, Wang J, Chau JF, Lai KP, Jia D, Poonepalli A, Hande MP, Liu H, He G, He L, Li B*. A positive role for c-Abl in Atm and Atr activation in DNA damage response. Cell Death Differ, 2011; 18(1):5-15.(IF: 9.050, Nature Publishing Group 杂志)
9. HY Kua, H Liu, WF Leong, L Li, D Jia, G Ma, Y Hu, X Wang, J F. L. Chau, YG Chen, Y Mishina, S Boast, J Yeh, L Xia, GQ Chen, L He, SP. Goff and B Li*. c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression. Nature Cell Biol, 2012; doi:10.1038/ncb2528.
10. Zou K, Hou L., Sun K., Xie W., Wu J.*Improved Efficiency of Female Germline Stem Cell Purification Using Fragilis-Based Magnetic Bead Sorting. Stem Cells and Development, 2011; 20: 2197-2204.(IF: 4.791)
11. Xiong J., Wang H., Guo G., Wang S., He L., Chen H., Wu J.*. Male Germ Cell Apoptosis and Epigenetic Histone Modification Induced by Tripterygium wilfordii Hook F. PLoS ONE, 2011; 6: e20751.(IF: 4.411)
12. Zhang Y., Yang Z., Yang Y., Wang S., Shi L., Xie W., Sun K., Zou K., Wang L., Xiong J., Xiang J., Wu J.*Production of transgenic mice by random recombination of targeted genes in female germline stem cells. Journal of Molecular Cell Biology,  2011; 3: 132-141.
13. Zou K., Yuan Z., Yang Z., Luo H., Sun K., Zhou L., Xiang J., Shi L., Yu Q., Zhang Y., Hou R., Wu J.*Production of offspring from a germline stem cell line derived from ovaries. Nature Cell Biology, 2009; 11: 631-636 (Table of Contents Cover Story).
14. Xuming Zhu, Huang Zhu, Lingling Zhang, Sixia Huang, Jingjing Cao, Gang Ma, Guoying Feng, Lin He, Yingzi Yang, Xizhi Guo*.Wls-mediated Wnts differentially regulate distal limb patterning and tissue morphogenesis. Developmental Biology, 2012; ;365(2):328-38. (IF: 4.094)

15. Xizhi Guo, Kingston Kunlun Mak, Makoto Taketo, Yingzi Yang*.The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One, 2009; 26;4(6):e6067.(IF: 4.411)
16. Chuwen Lin, Xuan Jiang, Zhongquan Dai, Xizhi Guo, Yinghui Li, Tujun Weng, Jun Wang, Guoyin Feng, Xiang Gao, Lin He*. Sclerostin Mediates Bone Response to Mechanical Unloading via Antagonizing Wnt/beta-Catenin Signaling. J Bone Miner Res, 2009; 24(10):1651-61.(IF: 7.056)
17. Zhu, M., Xin, T., Weng, S., Gao, Y., Zhang, Y., Li, Q., Li, M*.Activation of JNK signaling links lgl mutations to disruption of the cell polarity and epithelial organization in Drosophila imaginal discs. Cell Research, 2010; 20: 242-245.
18. Li, Q., Xin, T., Chen, W., Zhu, M., and Li, M*.Lethal(2)giant larvae is required in the follicle cells for formation of the initial AP asymmetry and the oocyte polarity during Drosophila oogenesis. Cell Research, 2008; 18:372-384.(This paper is the cover story on the issue)
19. Ma G, Yu J, Xiao Y, Chan D, Gao B, Hu J, He Y, Guo S, Zhou J, Zhang L, Gao L, Zhang W, Kang Y, Cheah KS, Feng G, Guo X, Wang Y, Zhou CZ, He L*.INDIAN HEDGEHOG mutations causing Brachydactyly Type A1 affect its signaling transduction at multiple steps. Cell Research, 2011; 21(9):1343-57.(IF: 9.417, Nature Publishing Group 杂志)

20. Lin An, Xiwen Zhao, Jian Wu, Jianguo Jia, Yunzeng Zou, Xizhi Guo, Lin He, Hongxin Zhu*.Involvement of autophagy in cardiac remodeling in transgenic mice with cardiac specific over-expression of human programmed cell death 5. PLoS One, 2012; 7(1):e30097. (IF: 4.411)

Note: The highest Impact Factors are quoted in brackets for reference only.