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Gang MA
Ph.D., Associate Professor, Deputy Principal Investigator
B.S. (1994-1998) Anhui Science and Technology University
M.D. (1998-2001) Changchun University of Agriculture and Animal Sciences
Ph.D. (2004-2007) Shanghai Jiao Tong University
Email: magang@sjtu.edu.cn |
INTRODUCTION:
Dr. Ma has won two golden medals of International Genetic Engineering Machine Competition (iGEM, a synthetic biology competition) as an instructor of SJTU-BIOX-SHANGHAI team in 2009 and 2010. In 2011, he has won the Best New Biobrick and Device (Asia Jamboree) award and the Sweet Sixteen award (World Jamboree). His works have been sponsored by NSFC and 973 programs.
RESEARCH INTERESTS:
The mechanism by which the IHH mutations cause Brachydactly type A1 (BDA1);
The role of Wnt, BMP and Hedgehog signaling pathways in the skin and hair follicle stem cell development;
Synthetic biology and the design of functional modules.
REPRESENTATIVE PUBLICATIONS:
Gang Ma#, Lili Li#, Yuanyu Hu, Jenny Fung Ling Chau, Bi Jin Au, Deyong Jia, Huijuan Liu, James Yeh, Lin He, Aijun Hao, and Baojie Li. Atypical Atm-p53 genetic interaction in osteogenesis is mediated by Smad1 signaling. Journal of Molecular Cell Biology (revised) Ma G, Yu J, Xiao Y, Chan D, Gao B, Hu J, He Y, Guo S, Zhou J, Zhang L, Gao L, Zhang W, Kang Y, Cheah KS, Feng G, Guo X, Wang Y, Zhou CZ, He L. INDIAN HEDGEHOG mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels. Cell Research. 2011; 21(9):1343-57. (Nature Publishing Group Journal) Gao B#, Hu J#, Stricker S, Cheung M, Ma G, Law KF, Witte F, Briscoe J, Mundlos S, He L, Cheah KS, Chan D. A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range. Nature. 2009; 458, 1196-1200. (Nature Publishing Group Journal) Ma G, Xiao Y, He L. Recent progress in the study of Hedgehog signaling. Journal of Genetics and Genomics. 2008; 35(3): 129-137. Ma G#, Shi Y#, Tang W, He Z, Huang K, Li Z, He G, Feng G, Li H, He L. An association study between the genetic polymorphisms within TBX1 and schizophrenia in the Chinese population. Neurosci Lett. 2007; 425(3):146-150. Ma G#, He Z#, Fang W, Tang W, Huang K, Li Z, He G, Xu Y, Feng G, Zheng T, Zhou J, He L, Shi Y. The Ser9Gly Polymorphism of the Dopamine D3 Receptor Gene and Risk of Schizophrenia: An Association Study and a large Meta-Analysis. Schizophrenia research. 2008; 101:26-35.
# Contributed equally to the paper
Study molecular mechanisms for brachydactyly type A1 and dactylaplasia; Study the function of signaling regulatory factors during bone development; Study the molecular mechanism of fracture healing.
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